Selective elimination of hypothalamic neurons by grafted hypertension- inducing neural tissue
نویسندگان
چکیده
منابع مشابه
Selective elimination of hypothalamic neurons by grafted hypertension-inducing neural tissue.
Embryonic hypothalamic tissue originating from spontaneously hypertensive rats (SHR) was implanted in young normotensive Wistar Kyoto rats in an attempt to localize hypothalamic regions directly responsible for the induction of hypertension. A 25% increase in host systolic blood pressure as compared with the controls was recorded 3 months after implantation in the animals receiving rostral hypo...
متن کاملPlasticity of GABAergic control of hypothalamic presympathetic neurons in hypertension.
Increased sympathetic outflow contributes to the pathogenesis of hypertension. However, the mechanisms of increased sympathetic drive in hypertension remain unclear. We examined the tonic GABAergic inhibition in control of the excitability of paraventricular (PVN) presympathetic neurons in spontaneously hypertensive rats (SHR) and normotensive controls, including Sprague-Dawley (SD) and Wistar-...
متن کاملO23: Differentiation of Human Neural Stem-Like Cells Derived from Epileptic Amygdala Tissue into Motor Neurons
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملAppetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons
Corticolimbic circuits involving the prefrontal cortex, amygdala, and ventral striatum determine the reward value of food and might play a role in environmentally induced obesity. Chemical manipulation of the nucleus accumbens shell (AcbSh) has been shown to elicit robust feeding and Fos expression in the hypothalamus and other brain areas of satiated rats. To determine the neurochemical phenot...
متن کاملDirected differentiation of neural cells to hypothalamic dopaminergic neurons.
Hypothalamic neurons play a key role in homeostasis, yet little is known about their differentiation. Here, we demonstrate that Shh and Bmp7 from the adjacent prechordal mesoderm govern hypothalamic neural fate, their sequential action controlling hypothalamic dopaminergic neuron generation in a Six3-dependent manner. Our data suggest a temporal distinction in the requirement for the two signal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1994
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.14-08-04891.1994